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Chox D.R. [1965]: A remark on multiple comparisons methods, Technometrics 7, 223-224 Cook S.A. [1971]: The complexity of theorem proving procedures, Proceedings of Third Annual ACM Symposium on Theory of Computing, 151-158 Craigh W. [1953]: On axiomatizability within a system, Journal of Symbolic Logic 18, 30-32 Cuda K. [1973]: Contributions to the theory of semisets III, Zeitschrift fr u mathematische Logik und Grundlagen der Mathematik 19, 399-406 Davis M. [1958]: Computability and unsolvability, New York Edwards A.W.F. [1963]: The measure of association in a 2 table, Journal of the Royal Statistical Society, ser. A 129, 109-114 Fabian V. [1968]: Statistische Methoden, Deutscher Verlag der Wissenshaften, Berlin Fagin R. [1973]: Contributions, the Model Theory of Finite Structures, Thesis, University of California, Berkeley Fagin R. [1974]: Generalized first-order spectra and polynomial time recognizable sets, Complexity of Computations ed. R.Karp, SIAM-ACM proceedings, vol. 7, 43-73 Fagin R. [1975a]: Monadic generalized spectra, Zeitschrift fr mathematische u Logik und Grundlagen der Mathematik 21, 89-96 Fagin R. [1975b]: A spectrum hierarchy, ibid., to appear ; Fergusson T.S. [1967]: Mathematical statistics, a decision theoretic approach, Academic Press, New York Fine T.L. [1973]: Theories of probability, Academic Press, New York Fisher M.S., Rabin M.O. [1974]: Super-exponential complexity of Presburger arithmetic, MAC Technical Memmorandum 43, MIT Fisher R.A. [1933]: The design of experiments, Oliver and Boyd, London Flum J. [1975]: First order logic and its extensions, ISILC-Logic Conference, Lect. Notes in Mathematics 499, Springer Verlag Fraisse R. [1965]: A hypothesis concerning the extension of finite relations and its verification in certain special cases, The theory of models, ed. J.W.Addison, L.Henkin, A.Tarski, 364-375 315. Annual Plan 2006-07 Objective Outcome Output [Physical Deliverable] 5 6 140 bedded Trauma To provide secondary health care services to the Centre to be patient with 500 beds to the residents of West commissioned. Delhi. To complete construction To provide Super Speciality Health Care Service work by September 2006. with 300 beds. Const. Work of 500 new To provide tertiary health care servicesto the ward block to be started. residents of Trans Yamuna Area and also imparting education to undergraduate and post graduate medicinal students. To complete 75% To provide super speciality construction work of the services with 650 beds. Hospital Building i.To meet establishment To provide expenditure. prisoners. ii.To purchase medicines machinery and equipment. health care medical care.
Cell Culture: Non-transformed human colonic epithelial NCM460 cells stably expressing NK-1R NCM460-NK-1R ; were made by a retroviral approach using the protocol described by us 20 ; These cells possess characteristics similar to native colonocytes, and have been used by us to study NK-1R signaling 20 ; . NCM460 and NCM460-NK-1R cells were cultured in M3D medium INCELL Corporation, San Antonio, CA, U.S.A. ; containing 10% FCS Invitrogen, Carlsbad, CA, U.S.A. ; , and 1% penicillin streptomycin Invitrogen ; solution. U373 MG astrocytoma cells, expressing high levels of endogenous NK-1R 27 ; , were obtained from ATCC Rockville, MD, U.S.A. ; and cultured in minimum essential medium MEM ; containing 10% FCS, 1% penicillin streptomycin solution, 25 mM sodium bicarbonate, and 10 mM sodium pyruvate Sigma, St. Louis, MO, U.S.A.

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Alignments for each of four different scoring functions to identify the function s ; and active site s ; of the protein encoded by each ORF, as previously described 40 ; . The genome sequences that aligned correctly to serine hydrolase structures in the structure library, according to the automated FFF match procedure, were identified as serine hydrolases and were further analyzed as described in the "Results" section. To determine confidence in the overall threading alignments, a standard Z-score was calculated. To determine confidence in FFF function assignments, active site profiling was used 45 ; . Briefly, experimental structures that display the particular functional activity described by an FFF true positive structures ; are aligned in threedimensional space. Then, superimposed sequence fragments surrounding the FFF motif in space illustrated in Fig. 1 ; are extracted from each structure and their sequences are aligned using CLUSTALW 46, 47 ; . This alignment of the fragments from the active site vicinity in known structures is termed an active site profile for a given function or FFF. For each predicted functional site, the local fragments around the FFF-identified active site residues are extracted, aligned with the active site profile from the structures known to exhibit the function, and scored against these active site profiles. Each residue position in the functional site profile is scored by identity, conservation, and the presence of a gap. For a gap-free alignment, the score varies from 0 to 1. When gaps are introduced into predicted functional site profiles, the score can fall below zero. High confidence function annotations have functional site profile scores greater than 0.25 45 ; . Function Identification Using Motif Databases--By definition an FFF serves as a template of the underlying chemical functionality of a protein, so equivalencies can be defined between FFFs and public tool motifs that describe the same or a related function; thus, motif equivalencies were established between FFFs and Pfam, BLOCKS and PRINTS motifs. The threading FFF results were compared with the results obtained using three sequence motif databases: PRINTS 20.0 48, 49 Pfam version 6.0 50, 51 and BLOCKS 52, 53 ; . These databases receive a sequence as input and output a list of sequence motifs ranked by score that may match the function of the query sequence. The top 10 hits by PRINTS and all query sequences above cutoff scores of 10 for Pfam and 5 for BLOCKS were analyzed to determine if the motifs identified a function equivalent to the FFFassigned function. In addition, BLAST 54, 55 ; was used to assign function based on annotation transfer. Function assignment is inferred from sequences with similarity to the query sequence. For this study, a cutoff value of 0.01 was used, to ensure that this analysis identified distantly related sequences.

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Persulfides thiuram disulfides 31 145; thiosulfonic acids 31 185 ; [2] . Aldehydes [2] Formaldehyde [2] . Ketones [2] acyclic [7] having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin [7] . Camphor; Nuclear substituted derivatives thereof [2] . Amines, e.g. amantadine 31 04 takes precedence ; [2] acyclic [7] having two or more amino groups, e.g. spermidine, putrescine [7] having hydroxy groups, e.g. sphingosine [7] having aromatic rings, e.g. methadone [2, 7] . having the amino group directly attached to the aromatic ring, e.g. benzeneamine [7] . Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine [7] . Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine atenolol 31 165; pindolol 31 404; timolol 31 5377 ; [7] Quaternary ammonium compounds, e.g. edrophonium, choline betaines 31 205 ; [2].

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Radioactive tracers and drugs to ovarian fluid from the blood in humans 9, 10 ; . follicular 1311 was and pitocin. Call the "unipolar" world. However, as they have long found out to their chagrin, an alternative global economic system may be a lot more difficult to create than, say, an Internet auction house.

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Drug Analysis: Penicillin concentrations were determined in all samples by HPLC with ultraviolet detection at 325 nm using an adapted version of previously published protocols Boison et al., 1991; Boison et al., 1992; Boison et al., 1994 ; . Penicillin V was used as the internal standard for all assays. Calibration curves were prepared by fortifying blank plasma, milk, muscle, liver, and kidney samples with known concentrations of penicillin G and penicillin V Sigma-Aldrich Canada Ltd, Oakville, ON, Canada ; . Two hexane flushes were performed on milk samples to extract fat present in the milk. Protein denaturation on all samples was performed with 5% sodium tungstate and 0.17 M sulfuric acid, followed by washing with 20% sodium chloride and vacuum filtering through a GF B filter. Samples were cleaned by solid phase extraction using Bond Elut C18 extraction cartridges Varian Inc, Lake Forest CA, USA ; preconditioned with methanol, water, and a 2% sodium chloride solution. After penicillin extraction the cartridges were washed with the same sodium chloride solution and water. Penicillin was eluted with 1.0 mL elution solution 5% 0.2 M phosphate buffer 35% water 60% ACN ; into clean glass tubes. 1.0 mL derivitizing reagent containing 1, 2, 4 Triazole and 0.01 M HgCl2 ; was added to the eluent and placed in a 65C water bath for 30 minutes. An HP1100 apparatus was used, consisting of a pump system equipped with an automatic injector 50 100 L sample ; and a UV variable-wavelength monitor at 325 nm. Separation was achieved by reverse-phase column Inertsil C8, 5 m, 150 4.6 mm, GL Sciences, Torrance, CA, USA ; . The mobile phase consisted of a mixture of 28% acetonitrile and 72% 0.05 M phosphate buffer and a flow rate of 1.2 mL min was used. Calibration curves were linear between 5 100, and 1000 10000 ng L for plasma, 5 100 and 100 500 ng L 58 and posture ANDROPAUSE men. J Clin Endocrinol Metab, 82: 2386, 1997 Zmuda, J. M., Cauley, J. A., Kriska, A. et al: Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants. J Epidemiol, 146: 609, 1997 Alexandersen, P., Haarbo, J. and Christiansen, C.: The relationship of natural androgens to coronary heart disease in males: a review. Atherosclerosis, 125: 1, 1996 Phillips, G. B., Pinkernell, B. H. and Jing, T. Y.: The association of hypotestosteronemia with coronary artery disease in men. Arterioscler Thromb, 14: 701, 1994 Uyanik, B. S., Ari, Z., Gumus, B. et al: Beneficial effects of testosterone undecenoate on the lipoprotein profiles in healthy elderly men. A placebo controlled study. Jpn Heart J, 38: 73, 1997 Morley, J. E., Perry, H. M., III, Kaiser, F. E. et al: Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study. J Geriatr Soc, 41: 149, 1993 Meikle, W. A., Stephenson, R. A., Lewis, C. M. et al: Effects of age and sex hormones on transition and peripheral zone volumes of prostate and benign prostatic hyperplasia in twins. J Clin Endocrinol Metab, 82: 571, 1997 Thomas, J. A. and Keenan, E. J.: Effects of estrogens on the prostate. J Androl, 15: 97, 1994 Behre, H. M., Bohmeyer, J. and Nieschlag, E.: Prostate volume in treated and untreated hypogonadal men in comparison to age-matched normal controls. Clin Endocrinol Oxf ; , 40: 341, 1994 Tenover, J. S.: Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab, 75: 1092, 1992 Tenover, J. L.: Androgen deficiency in aging men. Aging Male, suppl., 1: 16, 1998 Tenover, J. L.: Androgen supplementation in hypogonadal elderly men. Presented at Northeastern Section of American Urological Association, Toronto, Ontario, Canada, October 17 21, 1998 Nomura, A. Heilbrun, L. K., Stemmermann, G. N. et al: Prediagnostic serum hormones and the risk of prostate cancer. Cancer Res, 48: 3515, 1998 Cooper, C. S., Perry, P. J., Sparks, A. E. T. et al: Effects of exogenous testosterone on prostate volume, serum and semen prostate specific antigen levels in healthy young men. J Urol, 159: 441, 1998 Tenover, J. L.: Androgen deficiency in ageing male. Presented at the VI International Congress of Andrology, Salzburg, May 1997 93. Curran, M. J. and Bihrle, W., III: Dramatic rise in prostatespecific antigen after androgen replacement in a hypogonadal man with occult adenocarcinoma of the prostate. Urology, 53: 423, 1999 Tenover, J. L.: Testosterone and the aging male. J Androl, 18: 103, 1997 Sternbach, H.: Age-associated testosterone decline in men: clinical issues for psychiatry. J Psychiatry, 155: 1310, 1998 Sourial, N. and Fenton, F.: Testosterone treatment of an XXYY male presenting with aggression: a case report. Can J Psych, 33: 846, 1988 Christiansen, K.: Androgens, cognitive function and mood in men. In: Androgens and the Ageing Male. Edited by B. Oddens and A. Vermeulen. New York: Parthenon Publican Group, pp. 147165, 1996 98. Wang, C., Alexander, G., Berman, N. et al: Testosterone replacement therapy improves mood in hypogonadal men--a clinical research center study. J Clin Endocrinol Metab, 81: 3578, 1996 Morales, A., Bain, J., Ruijs, A. et al: Clinical practice guidelines for screening and monitoring male patients receiving testosterone supplementation therapy. Int J Impot Res, 8: 95, 1996 Tremblay, R. R. and Morales, A.: Canadian practice recommendations for screening, monitoring and treating men affected by andropause or partial androgen deficiency. Aging Male, 1: 213, 1998.

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In the philosophy of science, the demarcation problem is the decision between what constitutes science, i.e., astronomy, and distinguishes it from pseudoscience, astrology. This has a direct bearing on forensic science, inasmuch as certain disciplines are still considered scientifically "borderline" by some and it is important to sort out the science from the junk. Forensic science adds a novel wrinkle to the demarcation problem because, not only must it adhere to the definitions of science as understood by philosophers and practicing scientists la Kuhn ; , its science is applied in the legal arena where the home field provides a distinct advantage. Under Daubert, Courts act as gatekeepers, allowing "good" science to pass while barring the door to "bad" pseudoscience. This legal interpretation of what constitutes acceptable science, as seen in such rulings as Frye, Daubert, Kumho, and others, may or may not have any grounding in what scientists consider "good science" to be. The four conditions of Daubert are well known: general acceptability by the relevant scientific community, knowledge of the actual or potential rate of error for the practice, subjection of the practice to peer review, and actual or potential testability of the method's results. This final condition is an overt homage to Karl Popper's falsification model, which is referenced heavily in the Daubert court's decision. The Daubert decision is only one case law interpretation of Federal Rule 702 and not all philosophers of science agree that the Popperian approach is what defines science most accurately and, in fact, few adhere to this model today. Popper's model precludes any science that is not overtly oriented toward controlled laboratory experimentation, such as geology, astronomy, archaeology, and, to some extent, forensic science. This is because forensic science is partly a historical science, albeit dealing with very short time frames. 1 ; As has been noted 2 ; reference to known rates of error and testability presumes a model of science focused on controlled laboratory experimentation. Forensic scientists rarely have the luxury of controlled experimentation: Crimes cannot practically or ethically be reproduced under strictly proscribed conditions. Certain isolated events, such as discharging a firearm, identifying a controlled substance, or spattering blood, can be approximately repeated to allow for experimentation and these results are part of daily casework or publications in peer-reviewed journals. These results are not used, however, solely to further the growth of science but to reconstruct past events to determine causes, sources, and effects in crimes. This information, and other, is presented in court to assist the trier of fact. Of the possible competing hypotheses offered by the involved parties, one will be selected as more plausible by judge or jury, based in part on scientific conclusions and interpretations, leading to a legal decision. This duality of identity, empirical and historical, has probably led to the perception that forensic science is a lesser science or even "merely" a technique with no guiding philosophy. Historical disciplines have been derided as unscientific. 3 ; Legal rulings such as Kumho encourage this perception by reducing scientific disciplines with potentially sufficient supporting research to technical specialties that are unscientific and simply applications of "real" scientific principles. 4 ; Forensic science as a discipline is cheapened by the promulgation and reinforcement of this perception; resources of all kinds, from grants to budgets to public confidence, are reduced by the devaluing of the science in forensic science. But if Daubert isn't a proper definition of science and Kumho cheapens forensic science, what is to be done? The legal community and forensic science laboratories should seek more education on the nature of science and the underlying philosophy of forensic science. Forensic scientists should eschew the implications of current legal rulings and pursue research that will integrate the forensic science literature into a cohesive scientific foundation that will exceed the Kumho and even the Daubert framework. The information exists, the requirements are known, and the only obstacle that remains is our perception of forensic science as a lesser discipline.

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As described above, similar transport mechanisms for FL and FL-MTX were found in rat and dogfish shark CP. In the present study we examined transport of the medium-sized organic anion texas red TR ; in rat and dogfish shark CP and compared it with transport of FL and FL-MTX. Different to FL and FL-MTX transport, TR transport is different in both species. This is important due to the use of dogfish shark CP as a model for transport processes in mammalian CP. Dogfish shark CP was used by reason of its larger size, better accessibility, less fragility and longer viability in ex vivo experiments compared with rat CP. The ultrastructure of rat and shark CP are similar to each other as described in results Villalobos et al., 2002 ; , but only little molecular and immunohistochemical information on shark CP is available. Interpretation of results obtained in shark CP depends on data from mammalians. In the study we found specific and concentrative transport mechanisms for TR in both species, rat and dogfish shark. But transport proteins involved in TR transport in CP seem to be different for both species. By confocal microscopy we could visualize TR transport from aCSF ER ; into blood across CP epithelium, TR accumulation was in vascular perivascular spaces and the interior of blood vessels epithelial cells medium. By the use of different modulators of organic anion transport, we could draw conclusions about transport proteins involved in TR transport and pramlintide.

A standard diet containing 135 mmol sodium day and 70 mmol potassium day with no diuretic therapy, urinary aldosterone 18-glucuronide ; excretion was elevated 78 nmol day; normal, 8 44 nmol day ; . Plasma aldosterone was not measured at that time. PRA was 2.2 ng mL h recumbent normal, 0.5 4.0 ; and 5.5 ng mL h upright normal, 1.0 6.0 ; . Urinary aldosterone excretion and PRA were hardly suppressed by a diet containing 300 mmol day sodium plus 0.5 mg 9 -fluorocortisol day for 3 days Fig. 1 ; . Although renin was normal, the patient was considered to have primary hyperaldosteronism. Renal arteriography revealed no stenoses. Urinary catecholamine excretion was normal. Adrenal venography was compatible with a leftsided adrenal adenoma, about 1.5 cm in diameter Fig. 1 ; . However, the relatively high PRA led us to first treat the patient with drugs, including the aldosterone receptor blocker spironolactone. Administering 100 mg spironolactone twice daily, the initial dose we use in patients with primary hyperaldosteronism, led to hyperkalemia 6.9 mmol L ; and azotemia creatinine, 203 mol L ; . The spironolactone dose was reduced to 50 mg twice daily and combined with 150 g clonidine twice daily plus 25 mg hydrochlorothiazide in the morning. With this treatment, blood pressure ranged between 135 75 and 180 110 mm Hg until 1976. As spironolactone caused side-effects, we decided to explore the left adrenal and perform an intraoperative kidney biopsy. In September 1976, an adrenocortical tumor, 13 mm in diameter, with pathological features typical of an aldosteronoma was removed by left adrenalectomy Fig. 1 ; . The kidney biopsy showed arteriolosclerosis, hyalinized glomeruli, and interstitial fibrosis. Postoperatively, urinary aldosterone excretion was low normal 11.9 nmol day ; , and upright PRA ranged between 4 6 ng This result suggests that the tumor removed was an aldosteronoma and not an adrenal incidentaloma. Blood pressure control remained unsatisfactory until 1981, when minoxidil therapy 10 mg day; plus pindolol and furosemide ; was introduced. The blood pressure was then 130 150 70 mm Hg, serum potassium was 4.2 4.8 mmol L, and serum creatinine was 133150 mol L. However, the facial and leg edema that often accompanies treatment with minoxidil could not be fully controlled with diuretics. In 1993, minoxidil was replaced by 10 mg enalapril day plus 25 mg hydrochlorothiazide and 80 mg delayed action nifedipine ; . The now 61-yr-old patient feels well. His blood pressure is 130 150 70 mm Hg, with normal serum electrolytes and a serum creatinine level of 115 mol L. On this therapy, his PRA was 17.5 ng mL h and plasma aldosterone was 0.44 nmol L normal ; in July 1999.

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An example, should it be needed: here the topic discussed is the tendency to disequilibrium in the "balance of payments: " "I referring to the fall in international prices. If international prices go on falling year after year, the balance of payments, which tends to balance out after the first fall, is again unbalanced with successive falls . ; The case I considering is different. It involves the hypothesis that price levels fall continually over a number of years ; setting off a new wave of gold exports. That is the characteristic feature of this phenomenon" Prebisch [1991b] pp. 566, 569 and praziquantel.
Enjoy savings on pindolol canada from our dispensing pindolol online pharmacy. The absorption of dietary fat is an extremely efficient process resulting in 98% of dietary triglyceride being hydrolyzed and absorbed by the intestine. This has been attributed mainly to the action of PTL in the intestinal lumen. In fact, humans with PTL and colipase deficiency suffer from steatorrhea and deficiencies of fat-soluble vitamins and essential fatty acids 40, 41 ; . Therefore, it has generally been assumed that the high level of PTL release in response to a lipid-rich meal is sufficient to completely digest dietary fat. Interestingly, when and prevnar Medical facilities primarily for the diagnosis and treatment of a disease and injury; and 4 ; has a staff of Physicians licensed to practice medicine and provides 24 hour nursing care by graduate registered nurses. Psychiatric hospitals are not required to have a surgical facility. 1. Covered a. Room and board in a semi-private room or private room if room and board charges are the same as for a semi-private room general nursing care; medications, injections, diagnostic services and special care units. b. Attending Practitioner's services for professional care. c. Observation stays. d. Blood plasma is covered unless free. 2. Exclusions a. Inpatient stays primarily for therapy such as physical or occupational therapy ; . b. Maternity and delivery services, including complications of pregnancy. Benefits may be available under the HealthyTNBabies program. c. Services that could be provided in a less intensive setting. d. Private room when not authorized by the Plan and room and board charges are in excess of semi-private room. F. Hospital Emergency Care Services Medically Necessary and Appropriate health care services and supplies furnished in a Hospital which are required to determine, evaluate and or treat an Emergency until such condition is stabilized, as directed or ordered by the Practitioner or Hospital protocol. 1. Covered a. Medically Necessary and Appropriate Emergency services, supplies and medications necessary for the diagnosis and stabilization of Your Emergency condition. b. Practitioner services. 2. Exclusions a. Services received for inpatient care or transfer to another facility once Your medical condition has stabilized, unless Prior Authorization is obtained from the Plan within 24 hours or the next working day. G. Ambulance Services Medically Necessary and Appropriate land transportation, services, supplies and medications by a licensed ambulance service when time or technical expertise of the transportation is essential to reduce the probability of harm to You. 1. Covered a. Medically Necessary and Appropriate land or air transportation from the scene of an accident or emergency to the nearest appropriate facility. 2. Exclusions a. Transportation for Your convenience and pindolol.

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Craven, M. T., Payne, C. M., Powell, M. B., Gerner, E. W. & Earnest, D. L. 1998 ; Different bile acids exhibit distinct biological effects: the tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation. Nutr. Cancer 31: 111 8. Miettinen, T. A. 1982 ; Gas-liquid chromatographic determination of fecal neutral sterols using a capillary column. Clin. Chim. Acta 124: 245248. Morotomi, M., Guillem J. G., LoGerfo, P. & Weinstein I. B. 1990 ; Production of diacylglycerol, an activator of protein kinase C, by human intestinal flora. Cancer Res. 50: 35953599. Narisawa, T., Magadia, N. E., Weisburger, J. H. & Wynder, E. L. 1974 ; Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N -nitro-N-nitrosoguanidine in rats. J. Natl. Cancer Inst. 53: 10931097. National Public Health Institute 1998 ; The 1997 Dietary Survey of Finnish Adults. B8 1998, p. 57. Hakapaino Oy, Helsinki, Finland. Nishizuka, Y. 1992 ; Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science Washington, DC ; 258: 607 614. Owen, R. W., Henly, P. J., Tompson, M. H. & Hill, M. J. 1986 ; Steroids and cancer: fecal bile acid screening for early detection of cancer risk. J. Steroid Biochem. 24: 391394. Phan, S.-C., Morotomi, M., Guillem, J. G., LoGerfo, P. & Weinstein, I. B. 1991 ; Decreased levels of 1, 2-sn-diacylglycerol in human colon tumors. Cancer Res. 51: 15711573. Platz, E. A., Giovannucci, E., Rimm, E. B., Rockett, H.R.H., Stampfer, M. J., Colditz, G. A & Willet, W. C. 1997 ; Dietary fiber and distal colorectal adenoma in men. Cancer Epidemiol. Biomark. Prev. 6: 661 670. Preiss, J., Loomis, C. R., Bishop, W. R., Stein, R., Niedel, J. E. & Bell, R. M. 1986 ; Quantitative measurement of sn-1, 2-diacylglyserols present in platelets, hepatocytes, and ras and sis-transformed normal rat kidney. J. Biol. Chem. 261: 8597 8600. Rastas, M., Seppanen, R., Knuts, L.-R., Karvetti, R.-L. & Varo, P., eds. 1993 ; Nutrient Composition of Foods. Publications of the Social Insurance Institution, Helsinki, Finland. Reddy B. S. 1999 ; Role of dietary fiber in colon cancer: an overview. Am. J. Med. 106: 17S19S. Reddy, B. S., Narisawa, T., Weisburger, J. H. & Wynder, E. L. 1976 ; Promoting effect of sodium deoxycholate on colon adenocarcinomas in germfree rats. J. Natl. Cancer Inst. 56: 441 442. Reddy, B. S., Simi, B. & Engle, A. 1994 ; Biochemical epidemiology of colon cancer: effects of types of dietary fiber on colonic diacylglycerols in women. Gastroenterology 106: 883 889. Reddy, B. S. & Watanabe K. 1979 ; Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats. Cancer Res. 39: 15211524. Rowland, I. R. 1995 ; Toxicology of the colon: role of the intestinal microflora. In: Human Colonic Bacteria. Role in Nutrition, Physiology and Pathology Gibson, G. R. & McFarlane, G. T., eds. ; , pp. 155174. CRC Press, Boca Raton, FL. Ryhanen, E. L., Mantere-Alhonen, S. & Salovaara, H. 1996 ; Effects of oat bran and rye bran diet on intestinal lactobacillus and bifidobacterium flora of Wistar rats. In: COST Action 92 Dietary Fibre and Fermentation in the Colon. Proceedings of COST Action 92 Workshop Malkki, Y. & Cummings, J. H., eds. ; , pp. 5557. European Commission, Brussels, Belgium. Scheppach, W. 1998 ; Butyrate and the epithelium of the large intestine. In: Functional Properties of Non-Digestible Carbohydrates Guillon, F., Amado, ` R., Amaral-Collaco, M. T., Andersson, H., Asp, N. G., Bach Kudsen, K. E., Champ, M., Mathers, J., Robertson, J. A., Rowland, I. & Van Loo, J., eds. ; , pp. 215221. European Air Concerted Action AIR3CT94 2203, European CommissionDG XIIScience, Research and Development, Nantes, France. Schooley, D. L., Kubiak, F. M. & Evans, J. V. 1985 ; Capillary gas-chromatographic analysis of volatile and non-volatile organic acids from biological samples as the t-butyldimethylsilyl derivatives. J. Chromatogr. Sci. 23: 385 390. Stephen A. M. 1994 ; Whole grains--impact of consuming whole grains on physiological effects of dietary fiber and starch. Crit. Rev. Food Sci. Nutr. 34: 449 511. Stephen A. M. & Cummings J., H. 1980 ; The microbial contribution to human fecal mass. J. Med. Microbiol. 13: 4556. Stephen, A. M., Wiggins, H. S. & Cummings, J. H. 1987 ; Effect of changing transit time on colonic microbial metabolism in man. Gut 28: 601 609. Weisburger, J. H., Reddy, B. S., Rose, D. P., Cohen, L. A., Kendall, M. E. & Wynder E. L. 1993 ; Protective mechanisms of dietary fibers in nutritional carcinogenesis. Basic Life. Sci. 61: 45 63. Zhang, J.-X., Lundin, E., Hallmans, G., Adlerqreutz, H., Andersson, H., Boscaeus, I., man, P., Stenling, R. & Dahlgren, S. 1994 ; Effect of rye bran on excretion of bile acids, cholesterol, nitrogen, and fat in human subjects with ileostomies. Am. J. Clin. Nutr. 59: 389 394 and prialt.

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